Are blastocyst transfers more successful?Dr. Ashish Kale
The blastocyst transfer has given couples the opportunity to have healthier children with fewer birth defects and abnormalities. The use of blastocysts has resulted in a significant increase in the success rate of IVF treatment, according to researchers.
Blastocyst transfer is the most commonly used technique in IVF treatment. The cost of the procedure is usually included in the cost of the IVF treatment.
List of factors limiting the number of embryos that survive the Blastocyst transfer stage;
First, the embryo’s inherent health informs us about its ability to grow and divide. Some eggs may begin to fertilize, but only a few make it to the four-cell stage on the second day in culture. On the third day in culture, some still reach the eight-cell stage, and even fewer develop into a blastocyst. In layman’s terms, only the healthiest embryos will survive.
The culture media was the second factor that limited the growth of embryos in culture. Researchers identified the shortcomings of the in vitro culture environment and created new culture solutions, such as blastocyst media. These are high in life-sustaining nutrients, giving the embryos the best chance of developing naturally.
As a result, embryos are exposed to specific media designed to meet the nutritional needs of each stage of development beginning with egg collection.
Third, even embryos with the potential for good growth and better culture media require additional factors. Some of them include the knowledge and skill of the laboratory embryologists who handle this important work, which is critical to achieving good blastocyst development. As a result, it is critical to select the best laboratory that has obtained the most opportunities for patients in their IVF cycles to assist in the building of a family.
Benefits of Blastocyst Transfer
The use of embryo culture in IVF allows for the identification of embryos with the highest development efficiency. It also aids in maintaining embryonic age at the same time as endometrial, allowing for early communication between the two. This technique necessitates the use of more than one medium to meet the metabolic needs of the developing embryo.
Other advantages include:
- Blastocyst transfer is more physiological because the human embryo goes through several transformations. This occurs during the first four days of life, as the embryo grows and separates from a fertilized oocyte to the Blastocyst stage. It demonstrates changes in nutrient requirements and utilization, which aids in the formation of stage-specific culture media. It aids in the development of the embryo during the preimplantation period.
- The implantation rate in Blastocyst transfer is higher because the embryos have more time to develop in the laboratory. This makes it easier for the embryologist to select the embryo that will be implanted in the womb. According to the study, the success rate of blastocyst transfer based on clinical pregnancy rate is 43.4 per cent per blastocyst transfer.
- During the blastocyst transfer, a small number of embryos are transferred to the uterus. This reduces the likelihood of multiple pregnancies and increases the likelihood of success. As a result, only one or two embryos are implanted in the uterus. When two embryos are transferred, it results in multiple pregnancies in 25% of such cases because both embryos begin to develop.
- Preimplantation Genetic Diagnosis (PGD) is easier to perform on a blastocyst because more cells can be used for production and testing. PGD tests to aid in the elimination of faulty embryos and ensure that a good embryo free of genetic defects is transferred during the IVF procedure.
Blastocyst Transfer recommended for to whom?
IVF Specialist in Pune at Ashakiran Hospital will recommend Blastocyst Transfer to the couples who have repeatedly failed to conceive after transferring high-quality cleaved embryos (if the embryos are implanted and do not respond to a blastocyst, it may indicate a potential egg problem).
And also to those who want to become pregnant without the risk of having multiple pregnancies.
And Couples who do not want their extra embryos frozen.