The process of preparing the uterus for a frozen embryo transfer

Couples frequently use frozen embryos to increase their chances of becoming pregnant after a single IVF or ICSI round. When using frozen embryos, the embryos must first be thawed before being transferred to the uterus. A uterus can be prepared in three ways for the transfer of a thawed frozen embryo.


  1. Menstrual cycle in its natural state

The embryo can be transferred naturally if you ovulate frequently. We must monitor the growth of your eggs, the thickness of your endometrial lining (uterine lining), and your hormone levels to determine when the embryo should be transferred.

We can track the growth of your eggs and assess the thickness of your endometrial lining with a vaginal ultrasound. A blood test is required to determine hormone levels. Your embryo can be transferred if the follicle size, endometrial thickness, and hormone levels are all normal.

After the right amount of days, your embryo is placed in the uterus (six days later if a blastocyst is to be transferred or four days later if a day 3 embryo is to be transferred). There is a chance of natural pregnancy if you have intercourse during the cycle, in addition to the likelihood of embryo transfer success.


  1. Ovulation induction with FSH

FSH ovulation induction is a good option if you’re not ovulating regularly and have enough eggs in your ovary to ovulate.

FSH is a hormone injection that promotes the development of many eggs. Because of the danger of multiple pregnancies, you may be asked to refrain from sexual activity if two or more eggs mature in the ovary. If natural conception is possible, there is a possibility of twinning, just as there is with natural cycle FET. Injections of human chorionic gonadotropin (HCG) can trigger ovulation.


  1. The replacement of the hormones cycle.

If you’re not ovulating regularly, have a low quantity of good eggs, or are experiencing endometrial thickening, a hormone replacement cycle may be the best option for you.

To prevent egg formation from the ovary interfering with hormone levels, which impact the endometrial lining, a GnRH agonist (General) is often administered. Every three days, a table or patch is put to the skin to help thicken the endometrial lining. A second hormone, progesterone, is given vaginally once the endometrial lining has reached the desired thickness (Utrogestan, Endometrin or Crinone).

After the progesterone is started, the embryo is transferred to the uterus at the right moment. Pregnancy screenings are required via blood tests, and if the test is positive, hormones must be continued until the foetus is about eight or nine weeks old, at which point the placenta generates enough hormones to keep the pregnancy in place. After 10 weeks of pregnancy, the hormone dosages are gradually discontinued.


Motherhood- Awesome or Worrisome!!!

Being a mother is supposed to be the pinnacle of womanhood, at least according to popular belief. Motherhood offers a lot of happiness and fulfilment. However, those who have difficulty conceiving or are unable to conceive face additional challenges as a result of society’s ideas on parenting and femininity. We’d be focusing more on the joys and anxieties that pregnancy provides, as well as the challenges that infertility can bring.

It has been correctly stated,” You’ll always question whether you’re doing things incorrectly,” but that’s what it means to be a mother, to care so much about someone else that you just want to be as perfect as possible.”

Pregnancy brings a lot of changes to your life. Some of these feelings and emotions are pleasant, while others are disturbing and terrifying. You might possibly have troubles or other concerns that keep you awake at night.

When some women see a decrease in symptoms while pregnant, their anxiety may worsen. After all, you have no control over things that causes you anxiety. Hormonal changes during pregnancy may impact the chemicals in your brain. You may become worried as a result of this.

It’s natural to be concerned during pregnancy. After all, you may be unfamiliar with the procedure. You may have had experiences in the past, such as miscarriage, that made you nervous. However, if your worries begin to interfere with your daily life, you may be suffering from anxiety.

Among the signs and symptoms are:

  • Having an uncontrolled feeling of anxiety
  • Worrying excessively about things, particularly your health or the health of your child
  • An inability to focus
  • Feeling angry or irritable
  • Muscles that are tense
  • Sleeping in a bad way

Mild instances of anxiety normally don’t necessitate therapy; however, it’s a good idea to tell your doctor about your concerns. After assessing the benefits and hazards, your doctor may prescribe medication in severe circumstances.

It’s difficult to cope with infertility. However, we can make things more difficult for ourselves at times. Of course, not on purpose or purposefully. It’s possible we don’t realize it can be any other way. Or we’re simply unaware that we’re sabotaging ourselves.

It always seems impossible until its done. Infertility is just like any other medical condition that requires management by trained experts. Ashakiran Hospital tries to help you fill these shoes.

Though you may feel alone, and it may appear that you and your partner are the only infertile pair among your acquaintances, you are not alone in this vast universe. Fertility difficulties affect one out of every eight people at some point in their lives.

There’s a strong chance that someone you know has struggled with infertility and, like you, is keeping it hidden. Break the quiet by being brave. You can visit IVF Specialist in Pune at Ashakiran Hospital who can help you through the difficult emotions of infertility. They provide the best Infertility Treatment in Pune. So Don’t Hesitate and take the experience of Motherhood.

Infertility center in Pune

What is Ejaculation Disorder, and how does it affect you?

Ejaculatory dysfunction occurs when a man is unable to ejaculate effectively. It’s the most common type of male sexual dysfunction, and it’s frequently the root of infertility in men.

Disorders of the ejaculatory system are not uncommon. Premature ejaculation (PE) affects roughly 30-40% of men at some point in their lives. Premature Ejaculation is also reported by one in every five men aged 18 to 59, according to research.

Premature, delayed, retrograde, and ejaculatory dysfunction are the four forms of ejaculatory dysfunction. These disorders have various effects on ejaculation and can lead to sexual dissatisfaction.

  1. Premature Ejaculation

When a male ejaculates before or shortly after penetration, this is known as premature ejaculation (PE). Before orgasm, most men have ejaculation

Various reasons might cause premature ejaculation, including:

  • Hormone concentrations
  • Sensitivity of the sperm
  • Sexual arousal is low
  • Anxiety about performing

Premature Ejaculation can be treated in a variety of ways. Premature Ejaculation, like most sexual health issues, is treated differently depending on the reason. PE can be treated with physical therapy, psychotherapy, and medicines. The idea is to reduce penile sensitivity while improving a man’s capacity to manage his behavioural responses.

  1. Delayed Ejaculation (DE)

When a guy ejaculates after sexual stimulation, this is known as delayed ejaculation (DE).

DE happens from time to time, but it might become a concern if it happens frequently.

Delay in ejaculation can be caused by a variety of factors, including drugs, heavy alcohol use, diuretics, high blood pressure, and sexual performance anxiety. Hormonal abnormalities and low self-esteem can also contribute to DE.

  1. Retrograde ejaculation (RE)

When some or all of the ejaculate moves backwards, it is referred to as retrograde ejaculation (RE) (retrograde). Instead of coming out of the penis during the climax, the ejaculate returns to the bladder. It eventually passes via the kidneys during urination.

This ejaculation condition might lead to infertility if left unchecked. A malfunctioning bladder neck muscle is the most common cause of RE. The muscles can also be dysfunctional due to prostate or bladder surgery.

Medical diseases, such as diabetes or a spinal cord injury, as well as some drugs, can cause this harm. Prostate or bladder surgery can potentially cause muscular dysfunction.


  1. Anejaculation

Men who suffer from anejaculation usually take an exceptionally long time to ejaculate, while some never do. Anejaculation is a condition in which some men are unable to orgasm or ejaculate, while others can orgasm but not ejaculate. Men can also ejaculate without orgasm due to anejaculation.

Several causes can contribute to this ejaculatory dysfunction, including:

  • Hormonal imbalances
  • Ageing
  • Semen ducts clogged
  • Problems with the mind
  • Prescription drugs (SSRIs)
  • Diseases of the nervous system
  • Certain surgical procedures, including prostate and testicular cancer surgery, can also cause ejaculation.

If you’re having issues with erectile dysfunction, premature ejaculation or other sexual dysfunction, visit to Infertility center – Ashakiran Hospital and schedule an appointment to have a consultation with an experienced and one of the best IVF Specialist in Pune, Dr Ashish Kale.


Common Signs of Infertility in Women

Infertility occurs when a couple is unable to conceive after at least 12 months of regular unprotected intercourse.

Signs that Shows Infertility in Women:

Age: Around the age of 32, one’s ability to conceive begins to wane.

Sub mucosal fibroids: Submucosal fibroids are benign or non-cancerous tumours that develop in the uterine muscle wall, preventing sperm from fertilizing the egg. 

Endometriosis: Endometriosis is a condition in which the tissue that lines the uterus grows outside of the uterus. Endometriosis inflammation can harm sperm or eggs, preventing them from moving through the fallopian tubes and uterus. Adhesions or scar tissue may block the fallopian tubes in severe cases of endometriosis.

Tubal Infection, also known as Fallopian Tube Infection, is caused by the uncontrollable proliferation of malignant bacteria in the fallopian tubes. Streptococcus, Mycoplasma, and Staphylococcus are some of the microorganisms that cause tubal infection. Sexually transmitted illnesses (STDs) such as Chlamydia, Gonorrhea, and others can also cause the disease.

Radiation therapy has been linked to an increased risk of infertility. Autoimmune illnesses occur when the immune system of the body attacks normal body tissues that it would otherwise overlook. Lupus, Hashimoto’s thyroiditis, and other kinds of thyroiditis, as well as rheumatoid arthritis, can all impair fertility.


What are the most prevalent symptoms of Female Infertility?

  • Irregular menstrual cycles are a prominent indicator of reproductive difficulties.
  • Menstruation that is painful or heavy can be a sign of endometriosis. The disorder can produce painful inflammation and scarring, which can interfere with pregnancy and cause fertility issues.
  • Fertility difficulties might be indicated by the absence of menstruation.
  • Irritation of the skin can indicate a problem with fertility.
  • Reduced desire for sex
  • Hair growth on the face
  • Hair thinning
  • Excessive weight increase
  • Smoking
  • Alcohol use can influence a woman’s ability to conceive.
  • PCOS (polycystic ovarian syndrome) is a condition in which women do not ovulate or do so irregularly.
  • DOR (diminished ovarian reserve) 
  • FHA (functional hypothalamic amenorrhea) 
  • Primary ovarian insufficiency (POI), 
  • Menopause 
  • Hyperprolactinemia
  • Thyroid issues: 
  • Hormonal disorder


What are the risk factors linked to Infertility?

Women’s fertility falls as they get older.

Tobacco use: Smoking can lessen the chances of becoming pregnant. Women who smoke are more likely to have miscarriages.

Alcohol: Alcohol consumption has been linked to infertility.

Obesity: Living a sedentary lifestyle and being overweight can raise your chances of becoming infertile.

Depression and stress can have an impact on the hormones that control the reproductive cycle. Women who are struggling with these problems may not be able to ovulate regularly.


What are some suggestions for boosting fertility?

  • Maintain a healthy weight and consume a well-balanced, nutritious diet.
  • Tobacco and illegal narcotics should be avoided.
  • Consume alcohol in moderation or completely avoid it.
  • Get some moderate-intensity exercise regularly.
  • Avoid being exposed to toxins from the workplace or the environment.
  • Medicines that may impact fertility should be avoided.

If you are suffering from infertility problems please visit Ashakiran Hospital in Pune. 


All about ovulation cycles and tests

When a couple decides to have a baby, keeping track of the ovulation schedule becomes critical! This is due to the fact that a woman’s chances of conception are only present when she is ovulating. Knowing the specifics of ovulation cycles and having a basic understanding of determining the fertility window through and ovulation tests can improve your chances of conception.

Before delving into ovulation cycles, it’s a good idea to review the fundamentals.

What exactly is ovulation?

When a woman’s body releases one or more eggs from one of her ovaries, this is referred to as ovulation. It primarily occurs in the middle of the period cycle. Conception occurs when a fertile man’s sperm cell swims up through the vagina into the uterus and into a woman’s fallopian tube. It then merges with a female egg cell as it travels down one of the fallopian tubes.

The fertilized egg continues to move down the fallopian tube, dividing into two cells, then four cells, and so on as the division process continues. A week after fertilization, the fertilized egg enters the uterus and develops into a growing cluster of about 100 cells known as a blast cyst.

The cells continue to divide, with some developing into the baby and others forming the placenta, a structure that provides nourishment and oxygen to the baby. At the same time, hormones are released in the body, signalling that a baby is growing inside the uterus. The hormones also tell the uterus to keep its lining instead of shedding it. As a result, if a woman does not have her period during that month, it may be the first indication that she is pregnant. The presence of these hormones aids ovulation tests in their function.

Why is it critical for a woman to understand her fertility window?

Pregnancy is technically only possible if intercourse occurs during and around the time of ovulation. The three days preceding and including ovulation are the most fertile. Couples who have sex during this time period have the best chance of becoming pregnant. IVF Specialists can help you in the critical conditions.

A woman is no longer able to become pregnant 12-24 hours after ovulation because the egg is no longer in the fallopian tube. If a couple has intercourse before or after the fertile window, the chances of getting pregnant are almost nil. To be safe, contraception is still preferred.

How do you keep track of your ovulation cycle?

Although ovulation tests can be useful, noting the length of the menstrual cycle is the simplest way to determine the most fertile time. The fertile window is most likely to be between days 10 and 15. This should be followed by an examination of the body for signs of physical and hormonal changes.

Using cycle dates to determine the fertile window isn’t an exact science. This is where understanding the body’s fertile signs can come in handy. These are some examples:

Cervical mucus changes: Cervical mucus changes can indicate the fertility window. After a woman’s period has ended, her cervical mucus gradually increases in volume and texture.

An ache in the stomach: According to research, one-fifth of women can feel something happening in their ovaries during the ovulation period. This can range from mild aches to sharp pains.

Should a woman undergo ovulation testing?

When it comes to determining the fertility window or ovulation cycles, there are numerous tests on the market that can help determine whether or not one is ovulating. At Ashakiran Hospital, Ovulation tests detect the presence of the luteinizing hormone in the urine, which aids in determining ovulation. Hormone levels can skyrocket 12-36 hours before ovulation, assisting women in determining when the time is right.

One of the most important and beneficial tests is a follicular study, which is a Sevier of ultrasound that clearly indicates the period of ovulation. This requires a visit to a doctor so can visit to IVF Specialist in Pune at Ashakiran Hospital. To know more details about IVF treatment and related information, connect with us anytime as we are always there for you.

Can we see gynarcologist for fertility evaluation

Can we See Gynaecologist for Fertility Evaluation

Learning more about how Gynaecologist may treat infertility can benefit a patient who is trying to conceive but has had no luck so far. A gynaecologist can not only help a patient who is having fertility issues but they can also be expected to be compassionate. Because a patient will be working closely with Gynaecologist to learn more about why they are having such problems, it is critical to select a medical professional with whom the patient feels at ease.

How does Gynaecologist perform fertility exams?

Knowing how Gynaecologist performs a fertility evaluation can make patients feel more at ease by letting them know what to expect. The patient must first provide a detailed medical history. Following that, the patient must inform the Gynaecologist of the pregnancy goals, which will allow the two to discuss and plan the pregnancy. Typically, blood tests and imaging evaluations are required to determine what fertility issues are preventing the patient from becoming pregnant.

Reasons for Fertility Problems

These are some of the more common reasons why a woman may be having fertility problems and thus having difficulty getting pregnant.


According to Healthline, submucosal fibroids, a type of fibroid that grows and bulges into the uterine cavity, increase the risk of infertility or pregnancy loss. If fibroids are present, their size and location are critical. There are several fibroid treatment options, including surgical myomectomy, laser myolysis, using an intrauterine device, and taking birth control pills.


Endometriosis is a medical condition in which endometrial tissue grows outside of the uterus, causing pain. This tissue problem occurs in four stages and is known to interfere with a woman’s ability to conceive. The majority of women who are diagnosed with endometriosis require treatment to correct their fertility issues. Surgery, in vitro fertilization, and hormone therapy are all options for endometriosis treatment.

Polycystic ovarian syndrome (PCOS)

The polycystic ovarian syndrome occurs when a woman’s oestrogen and progesterone levels are out of balance. This hormonal imbalance can eventually cause small cysts to form on the ovaries. While the cysts themselves are painless and harmless, the hormonal imbalances they cause frequently result in irregular ovulation. To treat polycystic ovarian syndrome, a woman must generally take one of three different types of medications that can lead to more regular ovulation.

Ready to make an appointment?

At Ashakiran Hospital, Gynaecologist can assist a woman who is having difficulty conceiving by determining the source of the problem. There are numerous medical issues that can make it difficult for someone to conceive, necessitating a thorough evaluation of the patient.

With such an evaluation, you can learn the cause of your fertility issues as well as your treatment options. Dr Ashish Kale who is IVF Specialist in Pune has extensive experience n Laparoscopy, Hysteroscopy, all kinds of pelvic surgeries and retroperitoneal dissections.



Pregnancy test after IVF frozen embryo transfer?

Every couple considers IVF to be an important procedure, and all parents hope to conceive during their first cycle. They must understand, however, that some couples may require more than one cycle to see positive results. After two weeks, a pregnancy test is performed to check the results of an IVF procedure. It usually takes 10-14 days to see the IVF results after an embryo transfer procedure.

Fresh embryos are transferred to the uterus in some IVF cycles, while frozen embryos can also be transferred. The frozen embryo is thawed prior to transfer, and the rest of the procedure is the same.

Pregnancy Test

The detection of Beta-hCG, a pregnancy hormone, is only possible after a successful embryo transfer. This hormone is very important in pregnancy tests and can tell us the outcome of the pregnancy. It is for this reason that doctors advise taking a blood pregnancy test to confirm the pregnancy.

Because the hCG level varies during pregnancy, you should not take a urine pregnancy test before two weeks of embryo transfer. It remains constant during the first stage but decreases in the event of a miscarriage.

What Do Pregnancy Tests Look For?

Doctors measure beta-human chorionic gonadotropin hormone during a pregnancy test. This hormone is produced by the embryo’s trophectoderm cells. Its production increases and becomes noticeable after the implantation.

After three to eight days, the embryo transfer procedure is completed. It indicates the presence of detectable levels of HCG production in your bloodstream. The amount of HCG produced increases as the pregnancy progresses. An average woman has 25 mIU HCG after ten days of ovulation, but it increases to 50 mIU after 12 days and doubles again after two weeks. This measurement differs from one woman to the next.

Home Pregnancy Tests and Blood Pregnancy Tests

To confirm the pregnancy, a blood test for HCG can be performed. When you go to the doctor for this test, they will be able to monitor and measure the presence of HCG in your blood. It is more accurate, trustworthy, and sensitive than a home pregnancy test.

People can also use a home pregnancy test or a urine test to determine their HCG level. The sensitivity varies from pregnancy test to pregnancy test. The home pregnancy test is only sensitive to 100 mIU and cannot detect levels below 75 mIU. You may not get an accurate result until after a few days of embryo implantation. If your test result is negative, repeat the test.

Ultrasound vs. HCG Test

Even after seeing a positive result, people who have had several IVF failures find it difficult to believe that they are finally pregnant. A low level of HCG can occur in normal pregnancies in some cases, and these babies are also normal and healthy. Instead of testing the HCG level, you can perform an ultrasound to confirm the pregnancy. After two weeks, they will perform an ultrasound scan to confirm the presence of the yolk and the gestational sac.

So, if an HCG test does not confirm pregnancy, an ultrasound scan can.

When Is the Best Time to Get a Pregnancy Test?

Many people are perplexed as to why they cannot test for HCG after one week of embryo transfer. It is due to the fact that it is illogical. A healthy pregnancy can be detected by a doctor when the HCG hormone begins to be produced. Any test performed before two weeks of embryo transfer will yield results similar to those provided by your doctor before 36 hours of egg collection. After 48 to 72 hours, doctors repeat HCG blood tests.

An increasing level of HCG indicates a healthy pregnancy, but if this does not occur, the pregnancy may be unworkable. If the person is bleeding, she should also have the test done because bleeding can occur in pregnant women. You should not be concerned if you experience spotting or bleeding. You can visit Ashakiran Hospital if you are facing the above problems and want to meet the IVF Specialist in Pune.

Common Myths Associated with Male Infertility

7 Most Common Myths Associated with Male Infertility

Indian society mostly saddles women with the responsibility of bearing children, which signifies it’s the female who is blamed for being infertile should there be a delay or absence in pregnancy. Today, we’re debunking such myths by presenting a must-know list of myths and facts about male infertility. Like – did you have any idea that being overweight could harm the quality of sperms and overall sperm production? Here’s Dr. Ashish Kale, who provides special treatment for  Male Infertility in Pune, lays forward the causes behind it. He says, “Male infertility can often be treated, but first it’s necessary to clear the taboos and certain myths and seek medical help.” 

  1. Myth:

The biggest myth surrounding infertility is that infertility could be a female problem. 

Fact: “This isn’t true. In fact, in about 40% of cases of infertility; the issue lies with the male. We do see numerous cases where thousands of tests for females are done but not a single semen analysis is done for the male partner.”

  1. Myth: Stress is one of the main causes of infertility. 

Fact: “False. Stress affects one’s drive but not the semen quality or quantity and thus won’t result in infertility. So, if the sexual relations are ok and a lady still doesn’t conceive, then medical help should be sought for both the partners.”

  1. Myth: Keeping the testicles cold will enhance semen quality. 

Fact: “False. Cooling testicles with ice isn’t only dangerous but ineffective too. However, wearing tight undergarments, and prolonged driving should be avoided because it raises the scrotal temperature and affects sperm quality. Also, heat and radiation from the prolonged use of a laptop on the lap and frequent use of hot tubs or saunas aren’t good for sperms and is proven by many studies to decrease the sperm count.”

  1. Myth: Only older men have infertility problems. 

Fact: “No, even young men can have severe infertility problems. Absence of sperms or very low sperm counts is often encountered at ages as young as 20.”

  1. Myth: Does smoking and drinking cause infertility in men? 

Fact: “Agreed. Quitting smoking and drinking alcohol moderately is helpful as both are known to make sperm toxic.”

  1. Myth: Nutritional supplements don’t help in enhancing sperm quality. 

Fact: “Anti-oxidants like vitamin C, Vitamin E, zinc, selenium do help up to some extent.”

  1. Myth: Mobile phones kept within the pocket radiate electromagnetic waves, which damage sperm quality. 

Fact: “Well, this can be not always true as these concerns are yet to be proven by larger studies.”

Dr. Ashish Kale – IVF Specialist in Pune is also the founder of Ashakiran Hospital – A Infertility Center in Pune. He continuously shares his knowledge with his clients and creating awareness in the society about various topics.

Open chat